Is It Safe To Drink Alcohol Whilst Taking Amoxicillin? Rehab Guide

Alcohol and Amoxicillin

Alcohol and Amoxicillin

Man is drinking alcohol and taking pills

Whilst it is not recommended to drink alcohol whilst taking a course of amoxicillin, it is not considered dangerous when consumed in moderation.

Whether you as an individual should drink any alcohol at all whilst taking amoxicillin really depends on your personal circumstances. Alcohol won’t stop amoxicillin from working, but it could delay your recovery and make the side effects associated with amoxicillin worse.

For this reason, it is recommended that you avoid alcohol whilst taking amoxicillin.

What is Amoxicillin, and what is it prescribed for?

Amoxicillin is a type of antibiotic medication commonly prescribed for the treatment of bacterial infections such as ear, throat, urinary and chest infections (including pneumonia). They do not treat virus-based illnesses and only work if the full course of medication is taken as prescribed.

Amoxicillin is usually very well tolerated by most, but it can cause some unpleasant side effects. Amoxicillin is also safe to take during pregnancy.

Amoxicillin capsules

Common Side effects of Amoxicillin include:

  • Nausea
  • Diarrhoea
  • Stomach cramps
  • Wind
  • Headaches
  • Dizziness
  • Lethargy

Around 1 in 10 people will suffer from one or more of the common side effects of amoxicillin. If you do suffer from any of these side effects, you should avoid alcohol. Please contact your doctor if any become troublesome.

A very small percentage of people (around 1 in 1000) may suffer from amoxicillin’s more serious side effects.

Serious side effects of Amoxicillin include:

  • Severe diarrhoea and stomach cramps, leading to blood and mucus in stools and/or dehydration
  • Pale coloured stools, dark urine and yellowing of the skin or the whites of the eyes (These are all warning signs of potential liver or gallbladder problems)
  • Bruising or discolouration of the skin
  • Joint or muscle pain that starts after 2 days of taking the medicine
  • A skin rash with circular red patches
  • Raised red rash, blistering/peeling of the skin
  • Wheezing
  • Coughing
  • Respiratory distress
  • Anaphylaxis (1)

These more severe side effects of amoxicillin indicate an intolerance to the medication or an allergic reaction. Medical help should be sought without delay.


The side effects reported above in red are symptoms of an allergic reaction to amoxicillin and can occur in as many as 1 in 15 people.

Anaphylactic shock can kill within minutes. In the event of any breathing problems, swelling or severe rashes occurring, emergency services should be contacted immediately (1)

Amoxicillin also causes disturbances to good bacteria in the gut and body This effect can last for a few weeks after finishing a course of amoxicillin, leading to prolonged gastrointestinal discomfort and in some cases the development of Thrush (a yeast type fungal infection)

Drinking alcohol can also prolong the side effects of amoxicillin; alcohol also disturbs healthy bacteria in the body and prevents the absorption of nutrients.

Taking a good quality probiotic, eating healthily and avoiding alcohol can help to restore your body’s natural balance more quickly.

Before taking Amoxicillin, advise your doctor if you suffer from any of the following:

  • Liver disease
  • Kidney disease
  • Alcoholism
  • Drug abuse
  • Taking prescription drugs or over the counter medications that your doctor is unaware of
  • Have previously suffered an allergic reaction to amoxicillin
  • Have recently had any vaccinations or are due to have any vaccinations (1) 

Alcohol compromises your immune system.

It is common knowledge amongst clinicians that there is a strong association between excessive alcohol use and compromised immunity.

Drinking alcohol frequently and to excess can make a person more susceptible to pneumonia, respiratory infections, sepsis, certain cancers and alcoholic liver disease. It can also cause complications with wound healing and cause postoperative complications and infections.

This is why you mustn’t drink more than the Chief Medical Officers safe drinking guidelines of no more than 14 units of alcohol spread evenly over a week, especially whilst taking amoxicillin.

If you have a severe infection, a respiratory-related infection or a post-operative infection, alcohol should ideally be avoided altogether to ensure the best chance of making a full recovery (2)

How long after taking Amoxicillin, can I drink alcohol?

It is recommended that you wait at least 72 hours after finishing a complete amoxicillin course before drinking alcohol. You should also ensure that you have completely recovered from your infection.

If you continue to suffer from any of amoxicillin side effects once you have finished the course of medication, you should wait until the side effects subside. Drinking alcohol on top of suffering from amoxicillin side effects will only prolong them and make them worse (3)

Can I take Amoxicillin if I am alcohol dependent?

Being alcohol dependent is a serious medical health condition which means that it is not safe for you to suddenly stop drinking without a full medical alcohol detox.

If you are alcohol dependent, you should advise your GP at the time of prescribing. Additional monitoring may be required throughout the course of your medication or a different antibiotic, or a stronger course may be considered more suitable.

Those that suffer from an alcohol use disorder (AUD) will also find it very difficult to completely abstain or moderate their alcohol consumption whilst taking a course of amoxicillin.

Binge drinking whilst taking amoxicillin can severely compromise your immune system for 24 hours post alcohol consumption.

Alcohol dependence and alcohol addiction are at the most severe end of the alcohol use disorder spectrum. Both are considered life-threatening, and both require specialist treatment to overcome.

If you need professional help for an alcohol problem, please call and speak with us at Rehab Guide today. We are experts in treating alcohol use disorders and can ensure that you access fast and effective treatment as a matter of urgency.



1. Amoxicillin: antibiotics to treat bacterial infections – NHS
2. Alcohol and the Immune System Sarkar, Ph.D., D.Phil., M. Katherine Jung, Ph.D., and H. Joe Wang, Ph.D. –





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